It’s OK to use an aerosol fiber optic duster, sometimes called an “air duster” or “canned air”, to clean keyboards and blow dust out of racks, but don’t use it on end-faces.
A dry aerosol blast will not remove wet liquid contamination such as fingerprint oils. It does not have static-dissipative properties so it may add static charges to the connectors.
Also, the fluid in the can may spray out in liquid form and freeze the end-face, causing humidity to condense out of the air.
Lastly, some of these products are flammable and can be quite dangerous in enclosed spaces.
Sticklers offers a duster product that offers an exceptional value and very high purity. However, even the Sticklers™ product is not recommended for use on fiber optic end faces.